Enabling broad access to best-in-class CRISPR tools
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Explore further
MAD7™ – a powerful, flexible, and cost-effective tool for precise genome modifications, designed to accelerate your R&D.
01
Affordable, Customized Licensing
MAD7 is available under a tailored license model, offering flexible terms to match your project’s scale and needs – without the restrictive fields and expensive fees often associated with other proprietary nucleases.
02
High Efficiency and Low Off-Target
Studies show MAD7 performs with strong on-target activity and reduced off-target effects, offering a reliable platform for genome-editing across a range of organisms.
03
Versatile and Precise
Using a unique TTTN PAM motif, MAD7 expands your genome-editing possibilities, allowing you to target sites previously unreachable by SpCas9. The result: greater flexibility in designing guides and making precise modifications.
04
Scalable Applications
From agricultural biotechnology and microbial engineering to human health and therapeutics, MAD7 lets you tackle a broad spectrum of genome-editing projects quickly and cost-effectively.
MAD7™ lets you innovate with flexibility and confidence – unlocking possibilities in fields from drug development to food ingredient and small molecule production.
MAD7 is a licensing offering originally developed by Inscripta. In April 2025, Inscripta merged with Manus to create a leader in industrial biomanufacturing, establishing a unique end-to-end platform for development, scale-up, and commercialization of bioalternative products.
While Manus advances its integrated and proven scale-up platform, the MAD7 licensing program continues as an independent, standalone service.
Fully supported by Manus, it ensures MAD7 remains a trusted, widely available resource for researchers and partners worldwide.
Get in touch with Rob Evans from our Business Development team for technical or licensing support and to explore how to access best-in-class CRISPR tools.
Discover MAD7™ – a flexible, cost-effective genome-editing tool designed to make R&D faster, simpler, and more accessible.
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